Cyplexinol® works through two mechanisms of action. First is the immunoprotective effect, providing rapid clinical benefits as fast as 7 days! The second mechanism of action is the osteoinductive effect – growing new bone and cartilage tissue.
The Bone Morphogenetic Proteins (BMPs) in Cyplexinol® naturally fight against inflammation, providing an immunoprotective effect against Interlukin-1 (IL-1) and Interlukin-6 (IL-6) activation and its downstream components:
- IL-1 is a pro-inflammatory cytokine, which activates NF-Kappa b transcription factor and matrix metalloproteinases (MMPs).
- IL-6 is a pro-inflammatory cytokine key in converting acute inflammation to chronic inflammation.
The BMPs in Cyplexinol® naturally protect against inflammatory pathways providing clinical benefits as fast as 7 days
In 1965, Dr. Marshall Urist, an orthopedic surgeon and head of bone research at UCLA, discovered a new protein complex in bone that contained BMPs. When introduced to mesenchymal stem cells, this complex stimulated and differentiated those stem cells into:
- Osteoblasts, which grow bone tissue.
- Chondrocytes, which grow cartilage.
Dr. Urist’s discovery gave rise to the birth of osteobiologics! First applied to orthopedic surgery for bone fusions and repairs, it was discovered that this unique BMP-complex can survive the hostile environment of the gut leading to oral usage. Cyplexinol® is the only oral ingredient that contains the powerful osteoinductive BMPs and growth factors clinically shown to grow new bone and cartilage tissue.